SCHEMBL13764307

SCHEMBL13764307

COc1ccc(NC(=O)CC(OC(=O)C(Cc2ccccc2)OC)C(C)=O)c(S(=O)(=O)O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
MAPT P10636 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
TP53 P04637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
ALDH1A1 P00352 4/20 0.38
ALOX15 P16050 1/20 0.38
POLB P06746 3/20 0.38
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12141660 0.85 CYP1A2 (0.40) MMP1MMP2MMP3PDE4APDE4B
SCHEMBL13764197 0.85 ALDH1A1 (0.39) MAPTTP53L3MBTL1ALDH1A1MTNR1B
SCHEMBL13798050 0.77 MMP1 (0.43) MMP1MMP2MMP3PDE4APDE4B
SCHEMBL13764200 0.76 ALDH1A1 (0.39) MAPTTP53L3MBTL1ALDH1A1MTNR1B
SCHEMBL12141645 0.74 KDM4E (0.35) PPARGPPARAALDH1A1POLBKMT2A
SCHEMBL13764189 0.74 CA1 (0.38) ALDH1A1POLBKMT2A
SCHEMBL12141427 0.74 ALDH1A1 (0.40) MAPTCYP1A2L3MBTL1ALDH1A1KMT2A
SCHEMBL12141395 0.74 HTT (0.36) MAPTCYP1A2CYP2C9L3MBTL1ALDH1A1
SCHEMBL13993763 0.73 POLB (0.35) MMP1MMP2MMP3PDE4APDE4B
SCHEMBL13764303 0.73 SRR (0.45) PPARGPPARAALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7557176-B2 Polyhydroxyalkanoic acid having vinyl, ester, carboxyl or sulfonic acid group and producing method therefor CANON KABUSHIKI KAISHA (JP) 2009-07-07 US disclosed
US-20080064828-A1 Polyhydroxyalkanoic Acid Having Vinyl, Ester, Carboxyl or Sulfonic Acid Group and Producing Method Therefor CANON KABUSHIKI KAISHA (JP) 2008-03-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080064828-A1 Polyhydroxyalkanoic Acid Having Vinyl, Ester, Carboxyl or Sulfonic Acid Group and Producing Method Therefor FAR1, ACSL4, ACAD11 MMP1 3073/4885MMP2 2363/4885MMP3 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.