Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13773158 | 0.75 | MMP1 (0.36) | ALDH1A1MMP1MMP2MMP3MMP8 | |
| SCHEMBL13812295 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL85557 | 0.74 | NPSR1 (0.35) | ALDH1A1 | |
| SCHEMBL9911480 | 0.72 | CA1 (0.44) | ALDH1A1 | |
| SCHEMBL20000490 | 0.72 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL12258957 | 0.71 | KMT2A (0.46) | — | |
| SCHEMBL4510179 | 0.65 | JAK2 (0.39) | ALDH1A1ALOX5HTR2CHTR2BMMP1 | |
| SCHEMBL84558 | 0.65 | ALDH1A1 (0.38) | ALDH1A1MMP1MMP13 | |
| SCHEMBL18611267 | 0.65 | ALOX5 (0.39) | ALDH1A1ALOX5 | |
| SCHEMBL8293473 | 0.65 | DPP4 (0.41) | ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563785-B2 | Quetiapine analogs and methods of use thereof | HYPNION, INC. (US) | 2009-07-21 | — | — | US | disclosed |