Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.31 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9911480 | 0.84 | CA1 (0.44) | ALDH1A1NPSR1CA1CA2SMN1; SMN2 | |
| SCHEMBL13773158 | 0.79 | MMP1 (0.36) | ALDH1A1NPSR1CA1CA2CA12 | |
| SCHEMBL24961528 | 0.79 | CA1 (0.33) | ALDH1A1CA1CA2SMN1; SMN2HPGD | |
| SCHEMBL25121305 | 0.77 | CA1 (0.32) | ALDH1A1CA1CA2HPGD | |
| SCHEMBL13799203 | 0.74 | GAA (0.33) | ALDH1A1CA1CA2HPGDCA12 | |
| SCHEMBL13764329 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL85557 | 0.74 | NPSR1 (0.35) | ALDH1A1NPSR1SMN1; SMN2LMNA | |
| SCHEMBL84997 | 0.72 | LMNA (0.40) | ALDH1A1NPSR1SMN1; SMN2HPGDLMNA | |
| SCHEMBL6697856 | 0.71 | ALDH1A1 (0.41) | ALDH1A1NPSR1CA1CA2SMN1; SMN2 | |
| SCHEMBL4070679 | 0.70 | NPSR1 (0.48) | ALDH1A1NPSR1CA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | DDT, CAT, CIP2A | ALDH1A1 77/4885NPSR1 1061/4885CA1 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.