Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.30 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19225804 | 0.84 | RECQL (0.38) | LMNAPDK2ALDH1A1RECQL | |
| SCHEMBL19821860 | 0.81 | LMNA (0.39) | LMNAMCL1POLBPDK2ALDH1A1 | |
| SCHEMBL2757969 | 0.80 | HPGD (0.42) | LMNAPOLBALDH1A1MAPTMAPK1 | |
| SCHEMBL3266351 | 0.78 | FAAH (0.45) | LMNAMCL1ALDH1A1RECQL | |
| SCHEMBL25735462 | 0.77 | — | — | |
| SCHEMBL444607 | 0.76 | LMNA (0.36) | LMNAMCL1POLBALDH1A1MAPT | |
| SCHEMBL22787027 | 0.75 | LMNA (0.50) | LMNAMCL1POLBPDK2ALDH1A1 | |
| SCHEMBL2075717 | 0.74 | TSHR (0.55) | LMNAALDH1A1MAPTRECQL | |
| SCHEMBL17660249 | 0.74 | HPGD (0.45) | LMNAALDH1A1MAPTRECQL | |
| SCHEMBL1950213 | 0.74 | L3MBTL1 (0.44) | LMNAPOLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166114-B | Cyclic tetramer compounds as inhibitors of proprotein convertase subtilisin/KEXIN type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| WO-2022199677-A1 | NOVEL COMPOUNDS USEFUL AS STING AGONISTS AND USES THEREOF | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-09-29 | — | — | WO | disclosed |
| WO-2021222767-A1 | CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS | GLYCOMIMETICS, INC. (US) | 2021-11-04 | — | — | WO | disclosed |
| US-9718825-B2 | N-(4-(azaindazol-6-yl)-phenyl)-sulfonamides and their use as pharmaceuticals | SANOFI (FR) | 2017-08-01 | — | — | US | disclosed |
| WO-2009089680-A1 | METHOD OF MODULATING MEMBRANE POTENTIAL OF A CELL | YANG DAN (CN) | 2009-07-23 | — | — | WO | disclosed |