SCHEMBL1950213

SCHEMBL1950213

CC(C)(C)OCCC(=O)Nc1cc(NC(=O)CCOC(C)(C)C)cc(NC(=O)CCOC(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
LMNA P02545 1/20 0.40
KMT2A Q03164 3/20 0.40
RAB9A P51151 3/20 0.40
NPC1 O15118 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1950782 0.89 HDAC8 (0.46) L3MBTL1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL1948050 0.88 HDAC8 (0.49) L3MBTL1HDAC3HDAC4HDAC1HDAC7
SCHEMBL1947889 0.81 AAK1 (0.47) L3MBTL1CYP2C19KMT2APOLBSMN1; SMN2
SCHEMBL28402061 0.76 LMNA (0.59) L3MBTL1HDAC3HDAC4HDAC1HDAC7
SCHEMBL1948604 0.75 LMNA (0.47) L3MBTL1HDAC3HDAC4HDAC1HDAC7
SCHEMBL13765205 0.74 LMNA (0.43) LMNAPOLBMAPTALDH1A1
SCHEMBL23396951 0.74 HDAC3 (0.60) L3MBTL1HDAC3HDAC4HDAC1HDAC7
SCHEMBL2757969 0.72 HPGD (0.42) HDAC2LMNAKMT2ARAB9ANPC1
SCHEMBL11798744 0.71 ALDH1A1 (0.58) L3MBTL1CYP1A2CYP3A4CYP2C9CYP2C19
SCHEMBL3266351 0.71 FAAH (0.45) L3MBTL1LMNAKMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1592738-B1 RESIN COMPOSITIONS CIBA HOLDING INC (CH) 2020-07-29 EP disclosed
US-9029446-B2 Clarified polypropylene articles with improved optical properties and/or increased temperature of crystallization BASF SE (DE) 2015-05-12 US disclosed
EP-2510047-B1 CLARIFIED POLYPROPYLENE ARTICLES WITH IMPROVED OPTICAL PROPERTIES AND/OR INCREASED TEMPERATURE OF CRYSTALLIZATION BASF SE (DE) 2014-11-05 EP disclosed
US-8415416-B2 Electret materials BASF SE (DE) 2013-04-09 US disclosed
US-20130012091-A1 Electret Materials BASF SE (DE) 2013-01-10 US disclosed
US-20120184170-A1 Electret Materials CHIN HUI (US) 2012-07-19 US disclosed
US-20110230109-A1 Electret Materials CHIN HUI 2011-09-22 US disclosed
US-20110136950-A1 Clarified Polypropylene Articles with Improved Optical Properties and/or increased temperature of Crystallization BASF SE (DE) 2011-06-09 US disclosed
US-7790793-B2 Amide nucleating agent compositions CIBA SPECIALTY CHEM. CORP. (US) 2010-09-07 US disclosed
US-20080249269-A1 Electret materials CIBA CORP. 2008-10-09 US disclosed
US-20070149663-A1 Resin compositions CIBA SPECIALTY CHEMICALS CORP. 2007-06-28 US disclosed