Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MC5R | P33032 | 1/20 | 0.30 |
| ▸ | MC3R | P41968 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275274 | 0.80 | MAPT (0.34) | MEN1KMT2APOLBMAPTSIGMAR1 | |
| SCHEMBL1376734 | 0.77 | AOC3 (0.36) | ALDH1A1MAPTSIGMAR1 | |
| SCHEMBL274872 | 0.72 | SMN1; SMN2 (0.33) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL2595023 | 0.71 | LMNA (0.46) | MEN1KMT2AALDH1A1TRPM8MAPT | |
| SCHEMBL275273 | 0.70 | DRD2 (0.48) | POLBOPRD1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL2455720 | 0.69 | MEN1 (0.45) | MEN1KMT2AALDH1A1TRPM8MAPT | |
| Bromide SCHEMBL6625831 | 0.69 | MEN1 (0.45) | MEN1KMT2AALDH1A1TRPM8MAPT | |
| SCHEMBL276375 | 0.68 | SIGMAR1 (0.34) | MEN1KMT2AOPRD1KDM4ESIGMAR1 | |
| Hydrochloric Acid SCHEMBL27845404 | 0.68 | MEN1 (0.44) | MEN1KMT2AALDH1A1TRPM8MAPT | |
| SCHEMBL274458 | 0.68 | DRD2 (0.35) | MEN1KMT2AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4819280-B2 | — | — | 2011-11-24 | — | — | JP | claimed |
| JP-2004500426-A | — | — | 2004-01-08 | — | — | JP | claimed |
| EP-1274411-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | Axon Biochemicals B.V. (NL) | 2003-01-15 | — | — | EP | claimed |
| WO-2001078713-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | AXON BIOCHEMICALS B.V. (NL) | 2001-10-25 | — | — | WO | claimed |
| EP-1274411-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | Axon Biochemicals B.V. (NL) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001078713-A1 | PHENYLETHYLAMINES AND CONDENSED RINGS VARIANTS AS PRODRUGS OF CATECHOLAMINES, AND THEIR USE | AXON BIOCHEMICALS B.V. (NL) | 2001-10-25 | — | — | WO | disclosed |