Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944409 | 0.89 | EGFR (0.45) | EGFRPDGFRBKDRNQO1MAPT | |
| SCHEMBL1374260 | 0.82 | ACP1 (0.44) | EGFRPDGFRBKDRMAPTMEN1 | |
| SCHEMBL19018971 | 0.78 | NQO1 (0.47) | EGFRPDGFRBKDRNQO1MAPT | |
| SCHEMBL12412340 | 0.78 | CYP2A6 (0.53) | CYP1A2CYP2A6MEN1KMT2ALMNA | |
| SCHEMBL13241927 | 0.77 | ALDH1A1 (0.47) | MAPTCYP1A2CYP2A6AHRHPGD | |
| SCHEMBL9973887 | 0.76 | ALDH1A1 (0.41) | EGFRPDGFRBKDRMAPTMEN1 | |
| SCHEMBL7835437 | 0.76 | CYP2A6 (0.57) | EGFRPDGFRBKDRNQO1MAPT | |
| SCHEMBL13241087 | 0.76 | PDGFRB (0.46) | PDGFRBNQO1MAPTTUBB3CYP1A2 | |
| SCHEMBL25621958 | 0.74 | ACHE (0.59) | EGFRPDGFRBKDRMAPTTUBB3 | |
| SCHEMBL17702102 | 0.74 | HTT (0.48) | MAPTCYP1A2CYP2A6AHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623577-B2 | Acrylic ester compound and manufacturing intermediate thereof, method for manufacturing acrylic ester compound, and latent electrostatic image bearing member, image forming method, image forming apparatus and process cartridge | RICOH COMPANY, LTD. (JP) | 2014-01-07 | — | — | US | disclosed |
| US-20110287353-A1 | ACRYLIC ESTER COMPOUND AND MANUFACTURING INTERMEDIATE THEREOF, METHOD FOR MANUFACTURING ACRYLIC ESTER COMPOUND, AND LATENT ELECTROSTATIC IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287353-A1 | ACRYLIC ESTER COMPOUND AND MANUFACTURING INTERMEDIATE THEREOF, METHOD FOR MANUFACTURING ACRYLIC ESTER COMPOUND, AND LATENT ELECTROSTATIC IMAGE BEARING MEMBER, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE | C9, PAM, NAA15 | EGFR 1693/4885PDGFRB 2856/4885KDR 3088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.