Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.41 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 8/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975416 | 0.89 | APP (0.41) | ALDH1A1L3MBTL1ERN1MCL1HPGD | |
| SCHEMBL8944409 | 0.83 | EGFR (0.45) | ALDH1A1SLC16A3SLC16A1EGFRPDGFRB | |
| SCHEMBL1376772 | 0.76 | EGFR (0.45) | ALDH1A1L3MBTL1SLC16A3SLC16A1EGFR | |
| SCHEMBL10445929 | 0.74 | MAPT (0.41) | ALDH1A1L3MBTL1SLC16A3SLC16A1ERN1 | |
| SCHEMBL9973886 | 0.71 | MAOB (0.38) | ALDH1A1L3MBTL1PDGFRBLMNAKDM4E | |
| SCHEMBL30716563 | 0.70 | ERN1 (0.44) | ALDH1A1L3MBTL1ERN1MCL1LMNA | |
| SCHEMBL3269014 | 0.70 | ERN1 (0.55) | ALDH1A1ERN1MCL1LMNAHPGD | |
| SCHEMBL19018971 | 0.68 | NQO1 (0.47) | ALDH1A1L3MBTL1EGFRPDGFRBKDR | |
| SCHEMBL9163960 | 0.68 | ABL1 (0.46) | ALDH1A1L3MBTL1SLC16A3SLC16A1KDM4E | |
| SCHEMBL19275027 | 0.68 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1LMNAHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8546049-B2 | Electrophotographic photoconductor and image forming apparatus using the same | SHARP KABUSHIKI KAISHA (JP) | 2013-10-01 | — | — | US | disclosed |
| US-20120156600-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND IMAGE FORMING APPARATUS USING THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2012-06-21 | — | — | US | disclosed |