SCHEMBL1376900

SCHEMBL1376900

C=CS(=O)(=O)c1cc[c]c(S(=O)(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
TSHR P16473 1/20 0.39
XBP1 P17861 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
MDM2 Q00987 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.36
EPAS1 Q99814 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1373270 0.83 ALDH1A1 (0.41) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL15653727 0.78 NPC1 (0.41) NPC1ALDH1A1LMNATP53MAPT
SCHEMBL20838953 0.78 ALDH1A1 (0.35) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL27958319 0.78 ENPP2 (0.38) ALDH1A1LMNAMAPTTSHRSMN1; SMN2
SCHEMBL10479008 0.76 NPC1 (0.40) NPC1ALDH1A1LMNATP53MAPT
SCHEMBL15654298 0.76 NPC1 (0.40) NPC1ALDH1A1LMNATP53MAPT
SCHEMBL28057658 0.73 PARP1 (0.35) ALDH1A1LMNATSHRSMN1; SMN2HSD17B10
SCHEMBL15653832 0.73 TSHR (0.44) NPC1ALDH1A1LMNATP53MAPT
SCHEMBL9877646 0.72 CA2 (0.43) ALDH1A1HTT
SCHEMBL9743304 0.71 ALDH1A1 (0.37) NPC1ALDH1A1LMNATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0133283-B1 WATER-SOLUBLE DISAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-01 EP claimed
EP-1934293-B2 AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2020-12-09 EP disclosed
US-10190255-B2 Mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2019-01-29 US disclosed
US-10138596-B2 Mixtures of fiber-reactive azo dyes, their preparation and their use DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2018-11-27 US disclosed
EP-2391683-B1 FIBER-REACTIVE COPPER COMPLEX DISAZO DYES DYSTAR COLOURS DISTRIB GMBH (DE) 2017-03-29 EP disclosed
EP-2912119-B1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2016-12-14 EP disclosed
EP-2912118-B1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIB GMBH (DE) 2016-09-07 EP disclosed
US-20150284904-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-10-08 US disclosed
US-20150267345-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DYSTAR COLOURS DISTRIBUTION GMBH (DE) 2015-09-24 US disclosed
EP-2912118-A1 MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE DyStar Colours Distribution GmbH (DE) 2015-09-02 EP disclosed
US-5225544-A FIBER REACTIVE DYES WHICH CONTAIN A CYANOAMINOTRIAZINYL GROUP AND ONE OR TWO GROUPS OF THE VINYL SULFONE SERIES HOECHST AKTIENGESELLSCHAFT (DE) 1993-07-06 US disclosed
EP-0548792-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0548795-A2 Water-soluble reactive dyes, their manufacture and their use HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-30 EP disclosed
EP-0542214-A2 Water-soluble fibre-reactive dyes, process for their preparation and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
EP-0540554-A1 MONOAZO COMPOUNDS, METHOD OF PREPARING THEM, AND THEIR USE AS DYES. HOECHST AG (DE) 1993-05-12 EP disclosed
EP-0537220-A1 DIAZO COMPOUNDS, METHOD FOR PREPARING THEM, AND THEIR USE AS DYES. HOECHST AG (DE) 1993-04-21 EP disclosed
US-5138041-A Water-soluble fiber-reactive monoazo and disazo dyestuffs having a s-triazinylamino group and three fiber-reactive groups of the vinylsulfone series HOECHST AKTIENGESELLSCHAFT (DE) 1992-08-11 US disclosed
WO-1992001755-A1 MONOAZO COMPOUNDS, METHOD OF PREPARING THEM, AND THEIR USE AS DYES HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-06 WO disclosed
WO-1992001021-A1 DIAZO COMPOUNDS, METHOD FOR PREPARING THEM, AND THEIR USE AS DYES HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-23 WO disclosed
EP-0377166-A1 Water-soluble, fibre-reactive dyes, methods for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1990-07-11 EP disclosed