Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373459 | 0.81 | — | — | |
| SCHEMBL1373270 | 0.80 | ALDH1A1 (0.41) | CA2ALDH1A1 | |
| SCHEMBL20838953 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27958319 | 0.75 | ENPP2 (0.38) | ALDH1A1 | |
| SCHEMBL1376900 | 0.72 | NPC1 (0.39) | ALDH1A1HTT | |
| SCHEMBL1962068 | 0.72 | CA2 (0.59) | CA2POLBLOXALDH1A1HTT | |
| SCHEMBL28057658 | 0.71 | PARP1 (0.35) | CA2ALDH1A1 | |
| SCHEMBL12336517 | 0.70 | CA2 (0.67) | CA2POLBLOXALDH1A1HTT | |
| SCHEMBL10880757 | 0.69 | PSIP1 (0.43) | POLBALDH1A1 | |
| SCHEMBL9325260 | 0.69 | CA2 (0.78) | CA2POLBLOXALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171611-B1 | SUBSTITUTED PHENYLOXETHYL SULPHONES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | claimed |
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0171611-B1 | SUBSTITUTED PHENYLOXETHYL SULPHONES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |