Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | NQO1 | P15559 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228412 | 0.85 | KCNA3 (0.62) | LMNAALDH1A1SMN1; SMN2MAOANQO1 | |
| SCHEMBL5691199 | 0.85 | KCNA3 (0.62) | LMNAALDH1A1SMN1; SMN2MAOANQO1 | |
| SCHEMBL5396825 | 0.83 | NQO1 (0.67) | LMNAALDH1A1SMN1; SMN2MAOANQO1 | |
| SCHEMBL14424518 | 0.79 | LMNA (0.50) | LMNAALDH1A1SMN1; SMN2MAOANQO1 | |
| SCHEMBL7124523 | 0.78 | ALDH1A1 (0.55) | LMNAALDH1A1SMN1; SMN2CA1TNKS | |
| SCHEMBL13769543 | 0.78 | CA12 (0.70) | LMNAALDH1A1MAOANQO1KCNA3 | |
| SCHEMBL14424517 | 0.78 | CA12 (0.61) | LMNAALDH1A1SMN1; SMN2MAOACA12 | |
| SCHEMBL30228452 | 0.78 | ALDH1A1 (0.59) | LMNAALDH1A1SMN1; SMN2MAOANQO1 | |
| SCHEMBL31089772 | 0.76 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2MAOANQO1 | |
| SCHEMBL17059027 | 0.76 | MAPT (0.51) | LMNAALDH1A1SMN1; SMN2MAOAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1709699-B1 | CONJUGATED POLYMERS, REPRESENTATION THEREOF, AND USE OF THE SAME | MERCK PATENT GMBH (DE) | 2009-07-01 | — | — | EP | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |
| US-20070123690-A1 | Conjugated polymers, representation thereof, and use of the same | MERCK PATENT GMBH (DE) | 2007-05-31 | — | — | US | disclosed |