Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30228412 | 0.83 | KCNA3 (0.62) | ALDH1A1LMNASMN1; SMN2MAOANQO1 | |
| SCHEMBL5691199 | 0.83 | KCNA3 (0.62) | ALDH1A1LMNASMN1; SMN2MAOANQO1 | |
| SCHEMBL31089799 | 0.82 | CA12 (0.51) | ALDH1A1LMNASMN1; SMN2MAOANQO1 | |
| SCHEMBL20848059 | 0.82 | CA12 (0.61) | ALDH1A1LMNAMAOACA12CA9 | |
| SCHEMBL5396825 | 0.80 | NQO1 (0.67) | ALDH1A1LMNASMN1; SMN2MAOANQO1 | |
| SCHEMBL14424530 | 0.80 | ALDH1A1 (0.58) | ALDH1A1LMNASMN1; SMN2MAOAKCNA3 | |
| SCHEMBL9845372 | 0.78 | GABRP (0.58) | MAOANQO1CA12CA9CA1 | |
| SCHEMBL13769007 | 0.76 | LMNA (0.59) | ALDH1A1LMNASMN1; SMN2MAOANQO1 | |
| SCHEMBL14424526 | 0.76 | GABRP (0.50) | LMNANQO1CA12CA9CA1 | |
| SCHEMBL30228452 | 0.75 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2MAOANQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240252454-A1 | COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION | LEAD DISCOVERY CENTER GMBH (DE) | 2024-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240252454-A1 | COMPOSITION COMPRISING AN INHIBITOR OF MITOCHONDRIAL TRANSCRIPTION | TFAM, POLRMT, TUFM | ALDH1A1 3415/4885LMNA 2116/4885SMN1; SMN2 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.