Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.64 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.64 |
| ▸ | FDPS | P14324 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7911320 | 0.89 | PARP10 (0.63) | PARP10PARP15FDPSMEN1KMT2A | |
| SCHEMBL12149855 | 0.89 | PARP10 (0.63) | PARP10PARP15FDPSMEN1KMT2A | |
| SCHEMBL3962253 | 0.87 | MAOB (0.61) | PARP15MEN1KMT2AMAOBNPC1 | |
| SCHEMBL7911237 | 0.85 | PARP10 (0.64) | PARP10PARP15FDPSMEN1KMT2A | |
| SCHEMBL7908641 | 0.84 | ALOX5 (0.55) | MAOBNPC1FFAR4MRGPRX4 | |
| SCHEMBL1376902 | 0.83 | PARP10 (0.56) | PARP10PARP15FDPSMEN1KMT2A | |
| SCHEMBL7907439 | 0.82 | MAOB (0.56) | FFAR1MAOBNPC1RAB9AFFAR4 | |
| SCHEMBL21924287 | 0.82 | MAOB (0.58) | PARP15MEN1KMT2AMAOBNPC1 | |
| SCHEMBL3191667 | 0.82 | MAOB (0.58) | PARP10PARP15MEN1KMT2AMAOB | |
| SCHEMBL7910785 | 0.81 | MAOB (0.59) | PARP15FFAR1MAOBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211234-B1 | BENZONITRILE COMPOUNDS WITH ETHER AND SULFIDE GROUPS WITH CARBOXY ACID | RHONE-POULENC RORER LIMITED (GB) | 2001-04-03 | — | — | US | disclosed |
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | disclosed |
| EP-0728128-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1996-08-28 | — | — | EP | disclosed |
| WO-1995013262-A1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE-POULENC RORER LIMITED (GB) | 1995-05-18 | — | — | WO | disclosed |