Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769528 | 0.88 | MEN1 (0.45) | LMNAMEN1KMT2AGAARECQL | |
| SCHEMBL13769384 | 0.82 | HIF1A (0.37) | LMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL13769769 | 0.78 | MEN1 (0.32) | LMNASLC6A3MEN1KMT2AGAA | |
| SCHEMBL14519470 | 0.77 | ALDH1A1 (0.30) | LMNAMEN1KMT2A | |
| SCHEMBL13769994 | 0.76 | DGAT1 (0.54) | — | |
| SCHEMBL2254836 | 0.76 | MEN1 (0.53) | LMNASMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL14299766 | 0.70 | PKM (0.39) | — | |
| SCHEMBL29319143 | 0.69 | MEN1 (0.49) | LMNAMEN1KMT2AGAARECQL | |
| SCHEMBL29319220 | 0.69 | MEN1 (0.48) | LMNAMEN1KMT2AGAARECQL | |
| SCHEMBL24273884 | 0.67 | MEN1 (0.46) | LMNAMEN1KMT2AGAARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081195-A1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |