Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13769224 | 0.89 | LMNA (0.41) | MEN1KMT2ALMNA | |
| SCHEMBL13769529 | 0.83 | HIF1A (0.37) | — | |
| SCHEMBL14518609 | 0.82 | LMNA (0.39) | MEN1KMT2ALMNA | |
| SCHEMBL13769236 | 0.78 | LMNA (0.34) | MEN1KMT2ASLC6A3LMNAGAA | |
| SCHEMBL14518843 | 0.78 | KMT2A (0.34) | MEN1KMT2A | |
| SCHEMBL2255527 | 0.78 | MEN1 (0.52) | MEN1KMT2ALMNAGAAHTT | |
| SCHEMBL13769993 | 0.78 | DGAT1 (0.54) | — | |
| SCHEMBL2255191 | 0.75 | DGAT1 (0.38) | KMT2ALMNAHTT | |
| SCHEMBL14794814 | 0.68 | OPRM1 (0.40) | KMT2ALMNAGAAHTT | |
| SCHEMBL13769528 | 0.66 | MEN1 (0.45) | MEN1KMT2ALMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081195-A1 | CARBAMOYL COMPOUNDS AS DGAT1 INHIBITORS 190 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |