Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13768840 | 0.79 | PGR (0.36) | PDK1PDK2PDK3PDK4PGR | |
| SCHEMBL13769269 | 0.79 | PDK1 (0.31) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL13770128 | 0.78 | AR (0.46) | PGRARLMNAMAPT | |
| SCHEMBL13768718 | 0.74 | AR (0.45) | PGRARLMNAMAPT | |
| SCHEMBL13796904 | 0.71 | PGR (0.37) | PDK1PDK2PDK3PDK4PGR | |
| SCHEMBL13770468 | 0.70 | PDK1 (0.40) | PDK1PDK2PDK3PDK4PGR | |
| SCHEMBL13769023 | 0.68 | PGR (0.43) | PGRARLMNAMAPT | |
| SCHEMBL13769017 | 0.68 | AR (0.44) | PGRARLMNAMAPT | |
| SCHEMBL13769015 | 0.67 | PDK1 (0.33) | PDK1PDK2PDK3PDK4PGR | |
| SCHEMBL13770298 | 0.67 | AR (0.52) | PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083266-A1 | 17-HYDROXY-19-NOR-21-CARBOXYLIC ACID-STEROID γ-LACTONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING THE DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |