Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.46 |
| ▸ | PGR | P06401 | 13/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.37 |
| ▸ | SHBG | P04278 | 2/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770472 | 0.84 | SHBG (0.47) | ARPGRLMNAMAPTNR3C2 | |
| SCHEMBL13770298 | 0.80 | AR (0.52) | ARPGRNR3C2 | |
| SCHEMBL13769270 | 0.78 | PDK1 (0.34) | ARPGRLMNAMAPT | |
| SCHEMBL13474778 | 0.76 | AR (0.45) | ARPGRLMNANR3C2SHBG | |
| SCHEMBL13770468 | 0.75 | PDK1 (0.40) | ARPGRSLC6A4NR3C1 | |
| SCHEMBL13768718 | 0.73 | AR (0.45) | ARPGRLMNAMAPTNR3C2 | |
| SCHEMBL13770653 | 0.71 | AR (0.48) | ARPGRLMNAMAPTNR3C2 | |
| SCHEMBL13474804 | 0.68 | AR (0.54) | ARPGRNR3C2SHBG | |
| SCHEMBL13797568 | 0.68 | AR (0.48) | ARPGRLMNAMAPTNR3C2 | |
| SCHEMBL6841030 | 0.67 | AR (0.77) | ARPGRLMNAMAPTSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083268-A2 | 17-(1'-PROPENYL)-17-3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |