Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770699 | 0.84 | MEN1 (0.43) | NPC1RAB9ACYP1A2ALDH1A1LMNA | |
| SCHEMBL12848741 | 0.77 | HTR1F (0.38) | HTR1FNPC1RAB9ATP53MAPT | |
| SCHEMBL12848849 | 0.76 | HTR1F (0.40) | HTR1FNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL12848853 | 0.75 | HTR1F (0.37) | HTR1FNPC1RAB9ATP53CYP1A2 | |
| SCHEMBL23528955 | 0.64 | HTR1F (0.74) | HTR1FNPC1RAB9ATP53CYP1A2 | |
| SCHEMBL23528943 | 0.64 | HTR1F (0.51) | HTR1FNPC1RAB9ATP53CYP1A2 | |
| SCHEMBL29764279 | 0.64 | HTR1F (0.51) | HTR1FNPC1RAB9ATP53CYP1A2 | |
| SCHEMBL15205496 | 0.64 | SNCA (0.46) | HTR1FNPC1RAB9ATP53CYP1A2 | |
| SCHEMBL27487339 | 0.61 | MEN1 (0.57) | NPC1RAB9ATP53CYP1A2CYP2C19 | |
| SCHEMBL5232592 | 0.60 | HCAR3 (0.57) | NPC1RAB9ATP53SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089305-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2009-07-16 | — | — | WO | disclosed |