Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848449 | 0.87 | RORC (0.36) | HTR1FNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL12848853 | 0.82 | HTR1F (0.37) | HTR1FNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL12848741 | 0.82 | HTR1F (0.38) | HTR1FNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL12848842 | 0.81 | — | — | |
| SCHEMBL3827961 | 0.79 | HTR1F (0.42) | HTR1FNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL3823169 | 0.79 | HTR1F (0.44) | HTR1FNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL5019752 | 0.78 | HTR1F (0.40) | HTR1FNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL5019762 | 0.77 | HTR1F (0.42) | HTR1FALDH1A1LMNATP53MAP3K5 | |
| SCHEMBL13770701 | 0.76 | HTR1F (0.38) | HTR1FNPC1MAPTRAB9AALDH1A1 | |
| SCHEMBL12848559 | 0.74 | TP53 (0.37) | NPC1MAPTRAB9ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110052643-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052643-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | TSLP, NFATC1, IL5 | HTR1F 3815/4885NPC1 1042/4885MAPT 1865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.