Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 10/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 9/20 | 0.39 |
| ▸ | CDK1 | P06493 | 6/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770701 | 0.84 | HTR1F (0.38) | NPC1CYP1A2RAB9ALMNAALDH1A1 | |
| SCHEMBL12848445 | 0.75 | MEN1 (0.38) | MEN1KMT2ARORCNPC1RAB9A | |
| SCHEMBL12848449 | 0.75 | RORC (0.36) | MEN1KMT2ARORCNPC1CYP1A2 | |
| SCHEMBL12848757 | 0.72 | MEN1 (0.43) | MEN1KMT2ARORCNPC1CYP1A2 | |
| SCHEMBL14222427 | 0.72 | MEN1 (0.43) | MEN1KMT2ARORCNPC1CYP1A2 | |
| SCHEMBL1780134 | 0.71 | IL2 (0.48) | MEN1KMT2ACDK2CCNA2CDK1 | |
| SCHEMBL14172604 | 0.70 | RAB9A (0.45) | MEN1KMT2ANPC1CYP1A2RAB9A | |
| SCHEMBL12848851 | 0.70 | ADORA2A (0.33) | MEN1KMT2ARORCNPC1RAB9A | |
| SCHEMBL627356 | 0.69 | IL2 (0.49) | MEN1KMT2ACDK2CCNA2CDK1 | |
| SCHEMBL12848953 | 0.69 | ADORA2B (0.44) | MEN1KMT2ACYP1A2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009089305-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2009-07-16 | — | — | WO | disclosed |