Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 11/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536366 | 0.87 | RAB9A (0.43) | APPKDM4CNPC1RAB9AKDM4E | |
| SCHEMBL3537723 | 0.76 | TP53 (0.45) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL14949940 | 0.76 | CREBBP (0.41) | APPP2RX3KDM4CNPC1RAB9A | |
| SCHEMBL3533285 | 0.73 | RAB9A (0.44) | KDM4CNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL3534072 | 0.71 | RAB9A (0.40) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL3768515 | 0.69 | ALDH1A1 (0.43) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL3773297 | 0.68 | ALDH1A1 (0.46) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL2849400 | 0.67 | ICAM1 (0.42) | P2RX3KDM4CNPC1RAB9AALDH1A1 | |
| SCHEMBL3540745 | 0.66 | TARBP2 (0.49) | NPC1RAB9AKDM4EALDH1A1GAA | |
| SCHEMBL28443797 | 0.66 | RXRA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740583-B1 | OXADIAZOLONE DERIVATIVES AS PPAR DELTA AGONISTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-07-01 | — | — | EP | disclosed |