Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | GPR88 | Q9GZN0 | 4/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13688412 | 0.89 | CTSK (0.46) | CTSKCTSSGPR88KLK5 | |
| SCHEMBL13688435 | 0.87 | CTSK (0.53) | CTSKCTSSGPR88 | |
| SCHEMBL13707846 | 0.87 | SYK (0.45) | CTSKCTSSGPR88KLK5BACE1 | |
| SCHEMBL8351985 | 0.87 | CTSK (0.47) | CTSKCTSSGPR88KLK5 | |
| SCHEMBL3220240 | 0.87 | GPR88 (0.45) | GPR88 | |
| SCHEMBL13770905 | 0.85 | GPR88 (0.45) | GPR88 | |
| SCHEMBL13693225 | 0.85 | CTSK (0.43) | CTSKCTSSGPR88KLK5CTSL | |
| Hydrochloric Acid SCHEMBL3210982 | 0.79 | GPR88 (0.46) | GPR88 | |
| SCHEMBL13711107 | 0.79 | CTSS (0.50) | CTSKCTSSGPR88BACE1CTSL | |
| SCHEMBL8353220 | 0.78 | SYK (0.51) | CTSKCTSSKLK5CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301486-B1 | IMIDAZOLIDINONES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2009-07-01 | — | — | EP | disclosed |