Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR88 | Q9GZN0 | 8/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.38 |
| ▸ | CTSD | P07339 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3220240 | 0.91 | GPR88 (0.45) | GPR88AOC3GPR139ATMMEN1 | |
| Hydrochloric Acid SCHEMBL3210982 | 0.85 | GPR88 (0.46) | GPR88GPR139ATMPOLB | |
| SCHEMBL13770904 | 0.85 | CTSK (0.47) | GPR88 | |
| SCHEMBL13711058 | 0.84 | CTSL (0.43) | GPR88CTSD | |
| SCHEMBL10174287 | 0.84 | CTSD (0.41) | GPR88CTSD | |
| SCHEMBL3213229 | 0.80 | MMP2 (0.46) | GPR88AOC3GPR139ATMMEN1 | |
| SCHEMBL13770899 | 0.77 | METAP2 (0.42) | GPR88GPR139ATMMEN1KMT2A | |
| SCHEMBL13980019 | 0.77 | GPR88 (0.45) | GPR88AOC3POLB | |
| SCHEMBL3214499 | 0.76 | GPR139 (0.54) | GPR139ATMMEN1KMT2APOLB | |
| SCHEMBL8244173 | 0.76 | GPR88 (0.45) | GPR88GPR139POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301486-B1 | IMIDAZOLIDINONES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORP (US) | 2009-07-01 | — | — | EP | disclosed |