SCHEMBL137718

SCHEMBL137718

Fc1ccc([Mg]Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3168096 0.97 CA1 (0.36)
Water SCHEMBL456925 0.97 CA1 (0.36)
SCHEMBL7758944 0.92 BCL2L1 (0.39)
SCHEMBL23467126 0.89 NOS3 (0.43)
SCHEMBL11543870 0.73 TDP2 (0.43)
SCHEMBL7771444 0.72 CYP3A4 (0.38)
Bromide SCHEMBL1656508 0.71 CA1 (0.40)
SCHEMBL3027928 0.71
SCHEMBL13499 0.71
SCHEMBL667921 0.69 CES2 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3495 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
CN-120058632-A Method for synthesizing aprepitant intermediate through hydrogenation 苏州乔贝迪医药科技有限公司 2025-05-30 CN claimed
CN-119798292-A Polycyclic fusion molecule containing oxygen, boron and nitrogen coordination bonds and preparation method thereof 华侨大学 2025-04-11 CN claimed
CN-119285931-A Preparation method of polyarylether phosphine oxide intrinsic type room temperature phosphorescent material 重庆理工大学 2025-01-10 CN claimed
CN-119060007-A Preparation and application of fluorescence donor capable of controllably releasing hydrogen sulfide and carbon monoxide 广西中医药大学 2024-12-03 CN claimed
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN claimed
CN-114874080-B Preparation method of 4,4' -difluorobenzophenone 绍兴久孚新材料科技有限公司 2024-08-02 CN claimed
CN-114409602-B Method for synthesizing alpha-keto acid by using oxalyl chloride and Grignard reagent as raw materials 武汉大学 2024-01-30 CN claimed
US-11751568-B2 Picolinamide compounds with fungicidal activity CORTEVA AGRISCIENCE LLC (US) 2023-09-12 US claimed
CN-116410238-A Sulfur-containing chiral bridged metallocene compound, and preparation and application thereof 中国石油天然气股份有限公司 2023-07-11 CN claimed
US-20020062040-A1 PRODUCTION METHOD OF CITALOPRAM, INTERMMEDIATE THEREFOR AND PRODUCTION METHOD OF THE INTERMEDIATE SUMIKA FINE CHEMICALS CO., LTD. (JP) 2002-05-23 US claimed
CN-1331685-A Process for the preparation of citalopram LUNDBECK & CO AS H (DK) 2002-01-16 CN claimed
EP-1125907-A2 Intermediates for the production of citalopram SUMIKA FINE CHEMICALS Co., Ltd. (JP) 2001-08-22 EP claimed
EP-1120397-A2 Process for preparing triazole derivative KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-08-01 EP claimed
WO-2001025201-A1 PROCESS FOR THE PREPARATION OF PAROXETIN INTERMEDIATE SMITHKLINE BEECHAM P.L.C. (GB) 2001-04-12 WO claimed
EP-1064286-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 2001-01-03 EP claimed
WO-1999064428-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 1999-12-16 WO claimed
EP-0704419-A1 PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-04-03 EP claimed
US-4956507-A GRIGNARD REAGENTS FROM P-HALOFLUOROBENZENE AND MAGNESIUM COUPLING TO FORM P,P*-DIFLUOROBIPHENYL PHILLIPS PETROLEUM COMPANY (US) 1990-09-11 US claimed
US-4524221-A REACTING A GRIGNARD REAGENT WITH SILYLATED CYANOHYDRIN, TREATING WITH AQUEOUS ACID MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-18 US claimed