SCHEMBL7758944

SCHEMBL7758944

Fc1ccc(-c2ccc([Mg]Br)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2L1 Q07817 1/20 0.39
BAD Q92934 1/20 0.39
MAOB P27338 1/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
PTPN1 P18031 1/20 0.33
ACHE P22303 1/20 0.33
MAPK14 Q16539 2/20 0.32
TXN P10599 1/20 0.31
ERCC1 P07992 1/20 0.31
ERCC4 Q92889 1/20 0.31
NOTUM Q6P988 1/20 0.31
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL137718 0.92
Water SCHEMBL456925 0.89 CA1 (0.36) CA1CA2CA7CA9PTPN1
Hydrochloric Acid SCHEMBL3168096 0.89 CA1 (0.36) MAOBCA1CA2CA7CA9
SCHEMBL23467126 0.82 NOS3 (0.43) CA1CA2CA7CA9PTPN1
SCHEMBL7771444 0.80 CYP3A4 (0.38) MAOBCA1CA2
SCHEMBL7758933 0.77 CYP11B2 (0.43) NOTUM
SCHEMBL11543870 0.77 TDP2 (0.43) CA1CA2
SCHEMBL10337645 0.76 BCL2L1 (0.55) BCL2L1BADMAOBNPC1RAB9A
SCHEMBL12562793 0.76 BCL2L1 (0.55) BCL2L1BADMAOBNPC1RAB9A
SCHEMBL197346 0.76 BCL2L1 (0.55) BCL2L1BADMAOBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711777-B1 Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds SHINETSU CHEMICAL CO (JP) 2001-04-04 EP disclosed
EP-0696591-B1 Process for preparing silacyclohexane-based liquid crystal compounds SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
EP-0673942-B1 Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds SHINETSU CHEMICAL CO (JP) 2000-11-08 EP disclosed
EP-0687678-B1 Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds SHINETSU CHEMICAL CO (JP) 2000-03-22 EP disclosed
EP-0670322-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 2000-01-19 EP disclosed
US-5693841-A Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-12-02 US disclosed
US-5641431-A Silacyclohexanone compound and a method of preparing a silacyclohexane-type liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-06-24 US disclosed
US-5582764-A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-12-10 US disclosed
EP-0711777-A1 Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-15 EP disclosed
US-5514824-A Process for preparing silacyclohexane-base liquid crystal compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-05-07 US disclosed
EP-0696591-A1 Process for preparing silacyclohexane-based liquid crystal compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-02-14 EP disclosed
EP-0687678-A1 Cyclohexanone compounds, process for preparing the same, and processes for preparing silacyclohexane-based liquid crystal compounds from the cyclohexanone compounds SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-12-20 EP disclosed
EP-0673942-A1 Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds Shin-Etsu Chemical Co., Ltd. (JP) 1995-09-27 EP disclosed
EP-0670322-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-09-06 EP disclosed
US-4060633-A Phenylalkanol nitriles MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-11-29 US disclosed