Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 16/20 | 0.88 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CHUK | O15111 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13772410 | 0.93 | KIF11 (1.00) | KIF11MAPTCHUK | |
| SCHEMBL13772408 | 0.91 | KIF11 (0.84) | KIF11MAPT | |
| SCHEMBL10253400 | 0.91 | KIF11 (1.00) | KIF11MAPTCHUKKDM4E | |
| SCHEMBL19785406 | 0.84 | KIF11 (0.81) | KIF11MAPT | |
| SCHEMBL29726991 | 0.82 | KIF11 (0.75) | KIF11MAPTKDM4E | |
| SCHEMBL10141055 | 0.82 | KIF11 (0.75) | KIF11MAPTKDM4E | |
| SCHEMBL4129954 | 0.80 | KIF11 (1.00) | KIF11CHUK | |
| SCHEMBL412032 | 0.80 | KIF11 (0.81) | KIF11CHUKKDM4E | |
| SCHEMBL29507666 | 0.80 | KIF11 (0.81) | KIF11CHUKKDM4E | |
| SCHEMBL4126997 | 0.79 | KIF11 (1.00) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170882-A1 | Methods and compositions | CYTOKINETICS, INCORPORATED | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170882-A1 | Methods and compositions | KIF5B, KIF5C, KIF2C | KIF11 10/4885MAPT 47/4885CHUK 3598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.