Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818825 | 0.80 | LTA4H (0.55) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL6067593 | 0.77 | KMT2A (0.57) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL425634 | 0.74 | KMT2A (0.54) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL27476119 | 0.74 | OPRK1 (0.66) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL27615083 | 0.74 | ALDH1A1 (0.40) | KMT2ATDP1HSD17B10MAPTALDH1A1 | |
| SCHEMBL12291744 | 0.73 | KMT2A (0.75) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL20769767 | 0.73 | KMT2A (0.64) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL12291743 | 0.72 | KMT2A (0.68) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL12657551 | 0.72 | KMT2A (0.45) | KMT2AMEN1OPRK1TDP1ESR2 | |
| SCHEMBL27291810 | 0.72 | SLC1A1 (0.45) | KMT2AMEN1ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2080511-A2 | Active agent delivery systems and methods for protecting and administering active agents | Shire LLC (US) | 2009-07-22 | — | — | EP | disclosed |