Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27636784 | 0.79 | EPHX1 (0.51) | ALDH1A1KMT2AHSD17B10ATMTSHR | |
| SCHEMBL29159315 | 0.77 | CTSK (0.43) | ATML3MBTL1 | |
| SCHEMBL29159299 | 0.77 | CTSK (0.43) | ATML3MBTL1 | |
| SCHEMBL28222599 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL13996825 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL1810782 | 0.74 | PRSS1 (0.47) | ALDH1A1KMT2AMAPTLMNAHTT | |
| SCHEMBL26047547 | 0.74 | ALDH1A1 (0.49) | ALDH1A1KMT2ALMNAATML3MBTL1 | |
| SCHEMBL13772744 | 0.74 | KMT2A (0.49) | ALDH1A1KMT2AMAPTLMNAHTT | |
| SCHEMBL27312654 | 0.73 | FOLH1 (0.49) | ALDH1A1KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL19490630 | 0.73 | PRSS1 (0.46) | ALDH1A1KMT2AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100390174-C | Methylamino-pterin derivative with inhibiting nitric oxide synthetase function | CHINESE PHARMACEUTICAL UNIV (CN) | 2008-05-28 | — | — | CN | disclosed |
| CN-1583746-A | Methylamino-pterin derivative with inhibiting nitric oxide synthetase function | CHINESE PHARMACEUTICAL UNIV (CN) | 2005-02-23 | — | — | CN | disclosed |