Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286080 | 0.83 | GPR119 (0.54) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL18124056 | 0.82 | ALDH1A1 (0.47) | HPGDEPHX1ALDH1A1MAPTRAB9A | |
| SCHEMBL1880401 | 0.80 | HPGD (0.51) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL21026298 | 0.79 | PDE4D (0.45) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL7273992 | 0.79 | HPGD (0.48) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL7512359 | 0.79 | GPR119 (0.56) | HPGDRECQLEPHX1GPR119 | |
| SCHEMBL31352385 | 0.78 | HPGD (0.47) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL20128944 | 0.77 | GPR119 (0.57) | HPGDRECQLGPR119HTT | |
| SCHEMBL31629738 | 0.77 | HPGD (0.49) | HPGDDPP4RECQLEPHX1GPR119 | |
| SCHEMBL30981287 | 0.77 | HPGD (0.49) | HPGDDPP4RECQLEPHX1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732917-B1 | SELECTED CGRP ANTAGONISTS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2009-07-29 | — | — | EP | disclosed |