Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ATM | Q13315 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350543 | 0.94 | CRHBP (0.55) | CRHBPCRHR2KMT2AATMMEN1 | |
| SCHEMBL15099992 | 0.87 | SMN1; SMN2 (0.48) | CRHBPCRHR2KMT2AATMMEN1 | |
| SCHEMBL25603436 | 0.83 | RAB9A (0.46) | CRHBPCRHR2KMT2AMEN1RAB9A | |
| SCHEMBL25602956 | 0.82 | SMN1; SMN2 (0.47) | CRHBPCRHR2KMT2AMEN1RAB9A | |
| SCHEMBL27068058 | 0.82 | SMN1; SMN2 (0.47) | CRHBPCRHR2KMT2AMEN1RAB9A | |
| SCHEMBL22064637 | 0.80 | SMN1; SMN2 (0.47) | CRHBPCRHR2KMT2AATMMEN1 | |
| SCHEMBL24086454 | 0.80 | MAPT (0.60) | CRHBPCRHR2KMT2AMEN1RAB9A | |
| SCHEMBL21533085 | 0.80 | PLG (0.51) | RAB9ASMN1; SMN2NPC1XIAPBIRC2 | |
| SCHEMBL22593900 | 0.80 | MAPT (0.60) | CRHBPCRHR2KMT2AMEN1RAB9A | |
| SCHEMBL14435680 | 0.80 | XIAP (0.48) | CRHBPCRHR2KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090181039-A1 | CONJUGATES WITH REDUCED ADVERSE SYSTEMIC EFFECTS | BRISTOL-MYERS SQUIBB COMPANY | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181039-A1 | CONJUGATES WITH REDUCED ADVERSE SYSTEMIC EFFECTS | EPCAM, FCGR2A, CD47 | CRHBP 2796/4885CRHR2 3748/4885KMT2A 1999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.