SCHEMBL1377544

SCHEMBL1377544

[c]1cc[c]n1-c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ATM Q13315 1/20 0.35
MGLL Q99685 1/20 0.35
HPGD P15428 1/20 0.35
GSK3A P49840 3/20 0.33
GSK3B P49841 3/20 0.33
GAA P10253 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MAPK1 P28482 2/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17186577 0.69 KDM4E (0.39) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL44283 0.65 CYP3A4 (0.32) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL1573901 0.63 ALDH1A1 (0.50) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL22068219 0.63 ALDH1A1 (0.50) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL30060869 0.63 ALDH1A1 (0.50) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL9360920 0.63
SCHEMBL1007068 0.59 KDM4E (0.35) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL6441333 0.58 NOTUM (0.40) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL2466051 0.58 LMNA (0.42) KDM4EL3MBTL1ATMMGLLHPGD
SCHEMBL576814 0.56 LMNA (0.67) L3MBTL1MGLLGAASIGMAR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4769461-B2 2011-09-07 JP claimed
US-7648738-B2 for photopolymerization; photography, relief imaging; color filters CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-19 US claimed
EP-1567518-B1 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA HOLDING INC (CH) 2009-01-14 EP claimed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US claimed
JP-2006516246-A 2006-06-29 JP claimed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP claimed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO claimed
US-7648738-B2 for photopolymerization; photography, relief imaging; color filters CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-01-19 US disclosed
EP-1567518-B1 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA HOLDING INC (CH) 2009-01-14 EP disclosed
US-20060241259-A1 Oxime ester photoinitiators with heteroaromatic groups CIBA CORPORATION 2006-10-26 US disclosed
EP-1567518-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS Ciba SC Holding AG (CH) 2005-08-31 EP disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
EP-0360088-B1 Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles ABBOTT LAB (US) 1995-03-08 EP disclosed
US-5252459-A Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles ABBOTT LABORATORIES (US) 1993-10-12 US disclosed
EP-0360088-A2 Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles ABBOTT LABORATORIES (US) 1990-03-28 EP disclosed
US-4728796-A Method for ionization of polymers MEDICAL COLLEGE OF WISCONSIN (US) 1988-03-01 US disclosed