SCHEMBL1007068

SCHEMBL1007068

[C]1N(c2ccccc2)C=CN1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MGLL Q99685 1/20 0.35
HPGD P15428 1/20 0.35
GSK3A P49840 3/20 0.33
GSK3B P49841 3/20 0.33
GAA P10253 2/20 0.33
SIGMAR1 Q99720 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPK1 P28482 2/20 0.32
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1009551 0.83 GSK3A (0.35) KDM4EHPGDGSK3AGSK3BGAA
SCHEMBL6682807 0.78 ALDH1A1 (0.31) GAA
SCHEMBL4272759 0.72 LMNA (0.42) MGLLHPGDSIGMAR1MEN1KMT2A
SCHEMBL15573667 0.67 GAA (0.32) GSK3AGSK3BGAASIGMAR1HTR3E
SCHEMBL6441333 0.65 NOTUM (0.40) KDM4EATML3MBTL1MGLLHPGD
SCHEMBL14658329 0.64 ALDH1A1 (0.43) KDM4EMGLLHPGDGAAMEN1
SCHEMBL1005445 0.64 ALDH1A1 (0.43) KDM4EMGLLHPGDGAAMEN1
SCHEMBL1006035 0.63 SIGMAR1 (0.42) SIGMAR1MEN1NPC1RAB9AKMT2A
SCHEMBL9360920 0.63
SCHEMBL7436462 0.61 NPC1 (0.36) KDM4EATML3MBTL1MGLLHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2826802-B1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORP (JP) 2021-03-10 EP disclosed
US-20180127520-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2018-05-10 US disclosed
EP-2739653-B1 METHODS OF POLYMERIZING SILANES AND CYCLOSILANES USING N-HETEROCYCLIC CARBENES AND METAL COMPLEXES HAVING N-HETEROCYCLIC CARBENE LIGANDS THIN FILM ELECTRONICS ASA (NO) 2018-01-10 EP disclosed
US-9850325-B2 Method for producing ring-opening metathesis polymer hydride, and resin composition ZEON CORPORATION (JP) 2017-12-26 US disclosed
EP-1534722-B1 RHODIUM AND IRIDIUM COMPLEXES MERCK PATENT GMBH (DE) 2017-03-22 EP disclosed
EP-2270063-B1 PROCESS FOR PRODUCING HYDROGENATED PRODUCT OF CYCLIC OLEFIN POLYMER PREPARED THROUGH RING-OPENING POLYMERIZATION ZEON CORP (JP) 2016-03-23 EP disclosed
US-20150051353-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION ZEON CORPORATION (JP) 2015-02-19 US disclosed
EP-2826802-A1 METHOD FOR PRODUCING RING-OPENING METATHESIS POLYMER HYDRIDE, AND RESIN COMPOSITION Zeon Corporation (JP) 2015-01-21 EP disclosed
US-8900654-B2 Methods of polymerizing silanes and cyclosilanes using N-heterocyclic carbenes, metal complexes having N-heterocyclic carbene ligands, and lanthanide compounds Thin Film Electronics, Inc. (NO) 2014-12-02 US disclosed
EP-2739653-A1 METHODS OF POLYMERIZING SILANES AND CYCLOSILANES USING N-HETEROCYCLIC CARBENES, METAL COMPLEXES HAVING N-HETEROCYCLIC CARBENE LIGANDS, AND LANTHANIDE COMPOUNDS Kovio, Inc. (US) 2014-06-11 EP disclosed
EP-1093475-B1 CATALYST FOR THE POLYMERISATION OF OLEFINS BOREALIS TECH OY (FI) 2004-11-17 EP disclosed
US-6815516-B2 HEAT RESISTANCE, SOLVENT SOLUBILITY ZEON CORPORATION (JP) 2004-11-09 US disclosed
US-20040133004-A1 Rhodium and iridium complexes MERCK PATENT GMBH (DE) 2004-07-08 US disclosed
US-6613851-B1 Cyclic carbene- eta -ligand complexes for catalysis of olefin polymerization. BOREALIS TECHNOLOGY OY (FI) 2003-09-02 US disclosed
US-20030050406-A1 Process for producing hydrogenated product of cyclic olefin polymer prepared through ring-opening polymerization ZEON CORPORATION 2003-03-13 US disclosed
US-20030018138-A1 Copolymer formed by ring -opening polymerization, product of hydrogenation of copolymer formed by ring-opening polymerization, and process for producing these ZEON CORPORATION (JP) 2003-01-23 US disclosed
EP-1275675-A1 COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, PRODUCT OF HYDROGENATION OF COPOLYMER FORMED BY RING-OPENING POLYMERIZATION, AND PROCESSES FOR PRODUCING THESE Zeon Corporation (JP) 2003-01-15 EP disclosed
US-6486264-B1 Process for producing hydrogenated ring-opening polymerization polymer of cycloolefin ZEON CORPORATION (JP) 2002-11-26 US disclosed
EP-1197509-A1 PROCESS FOR PRODUCING HYDROGENATED RING-OPENING POLYMERIZATION POLYMER OF CYCLOOLEFIN Nippon Zeon Co., Ltd. (JP) 2002-04-17 EP disclosed
WO-2000078826-A1 CATALYSTS BOREALIS TECHNOLOGY OY (FI) 2000-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040133004-A1 Rhodium and iridium complexes RPIA, SIRT5, INPP5B KDM4E 3717/4885ATM 2664/4885L3MBTL1 4657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.