Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 7/20 | 0.82 |
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.61 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.61 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.61 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | POLB | P06746 | 5/20 | 0.61 |
| ▸ | RECQL | P46063 | 5/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.61 |
| ▸ | XDH | P47989 | 5/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.61 |
| ▸ | APEX1 | P27695 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13056253 | 0.92 | POLH (0.78) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL824468 | 0.90 | POLH (1.00) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL9288825 | 0.89 | MEN1 (0.78) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL6140182 | 0.87 | POLH (0.80) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL30819258 | 0.87 | POLH (0.80) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL16682483 | 0.86 | POLH (0.77) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL13780248 | 0.85 | POLH (0.82) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL13552041 | 0.85 | MEN1 (0.76) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL9733297 | 0.84 | ABCB1 (0.76) | POLHMEN1KMT2ACYP1A2CYP1A1 | |
| SCHEMBL12636895 | 0.83 | CYP3A4 (0.74) | POLHMEN1KMT2ACYP1A2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090186110-A1 | GUAVA EXTRACT | OMNICA GMBH (DE) | 2009-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186110-A1 | GUAVA EXTRACT | SMPD4, GBA3, DPP4 | POLH 1425/4885MEN1 4716/4885KMT2A 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.