SCHEMBL824468

SCHEMBL824468

Cc1c(-c2ccc(O)c(O)c2)oc2cc(O)cc(O)c2c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLH Q9Y253 9/20 1.00
MEN1 O00255 7/20 0.75
KMT2A Q03164 7/20 0.75
KDM4E B2RXH2 5/20 0.75
HSD17B10 Q99714 5/20 0.75
CYP1A2 P05177 5/20 0.75
RECQL P46063 4/20 0.75
CYP3A4 P08684 4/20 0.75
MAPT P10636 4/20 0.75
ALOX5 P09917 4/20 0.75
IPMK Q8NFU5 4/20 0.75
IP6K2 Q9UHH9 4/20 0.75
CYP1A1 P04798 4/20 0.75
CYP1B1 Q16678 4/20 0.75
NOX4 Q9NPH5 4/20 0.75
POLB P06746 3/20 0.75
GAA P10253 3/20 0.75
TP53 P04637 3/20 0.75
CYP2C9 P11712 3/20 0.75
ALOX15 P16050 3/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13776268 0.90 POLH (0.82) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL6140182 0.89 POLH (0.80) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL30819258 0.89 POLH (0.80) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL13056253 0.88 POLH (0.78) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL16682483 0.87 POLH (0.77) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL27746111 0.86 MEN1 (0.94) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL30819237 0.86 MEN1 (0.80) POLHMEN1KMT2AKDM4EHSD17B10
SCHEMBL13552041 0.86 MEN1 (0.76) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL31507620 0.86 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10
Quercetin SCHEMBL17629824 0.86 MEN1 (1.00) POLHMEN1KMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115120522-A Composition containing luteolin and derivatives as effective components for promoting hair growth and application thereof 浙江熙正霖生物科技有限公司 2022-09-30 CN claimed
CN-117740961-A Compound analysis method of liquorice and liquorice probiotics fermentation preparation 北京中医药大学 2024-03-22 CN disclosed
CN-117098460-A Sweetener composition comprising mogrosides and uses thereof 弗门尼舍公司 2023-11-21 CN disclosed
US-20230367223-A1 SUBSTRATE PROCESSING COMPOSITION AND SUBSTRATE PROCESSING METHOD USING THE SAME SK INC. (KR) 2023-11-16 US disclosed
CN-116997263-A Sweetener compositions comprising siamenoside I and uses thereof 弗门尼舍公司 2023-11-03 CN disclosed
CN-116963609-A Sweetener composition comprising mogrosides and uses thereof 弗门尼舍公司 2023-10-27 CN disclosed
EP-4215522-A1 DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF Fondazione Istituto Italiano di Tecnologia (IT) 2023-07-26 EP disclosed
EP-4215522-A1 DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF Fondazione Istituto Italiano di Tecnologia (IT) 2023-07-26 EP disclosed
US-20220387615-A1 COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF DANMARKS TEKNISKE UNIVERSITET (DK) 2022-12-08 US disclosed
CN-115120522-A Composition containing luteolin and derivatives as effective components for promoting hair growth and application thereof 浙江熙正霖生物科技有限公司 2022-09-30 CN disclosed
US-20090304827-A1 Combinations of Ingredients Having Synergistic Anti-Inflammatory Effects KIM DARRICK S H L 2009-12-10 US disclosed
US-20090143317-A1 Quercetin Glycoside Composition and Method of Preparing the Same SUNTORY LIMITED (JP) 2009-06-04 US disclosed
WO-2009064485-A1 ANTIOXIDANT FLAVONOID DERIVATIVES TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2009-05-22 WO disclosed
US-20090083874-A1 PRODUCTION OF PROANTHOCYANIDINS TO IMPROVE FORAGE QUALITY THE SAMUEL ROBERTS NOBLE FOUNDATION 2009-03-26 US disclosed
US-20090074708-A1 Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B) NATIONAL DEFENSE MEDICAL UNIVERSITY (TW) 2009-03-19 US disclosed
US-20080293644-A1 GUAVA EXTRACT OMNICA GMBH (DE) 2008-11-27 US disclosed
US-20080214493-A1 Use of Flavone Compounds as Potassium Channel Inhibitors VERSITECH LIMITED (CN) 2008-09-04 US disclosed
US-20080187622-A1 Method for manufacturing alpha-glycosylisoquercitrin, intermediate product and by-product thereof SAN-EI GEN F.F.I., INC. (JP) 2008-08-07 US disclosed
US-20080182893-A1 Prevention, therapy atherosclerosis; prevent plaque destabilization; using ienzyme modified soquercitrin SAN-EI GEN F.F.I., INC. (JP) 2008-07-31 US disclosed
US-20070248700-A1 Extractions and Methods Comprising Elder Species HERBALSCIENCE NUTRACEUTICALS, LLC 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090083874-A1 PRODUCTION OF PROANTHOCYANIDINS TO IMPROVE FORAGE QUALITY QPCTL, FABP6, HHAT POLH 2017/4885MEN1 2562/4885KMT2A 2296/4885
US-20080293644-A1 GUAVA EXTRACT DPP4, DPP8, DPP3 POLH 4197/4885MEN1 3603/4885KMT2A 2143/4885
US-20080214493-A1 Use of Flavone Compounds as Potassium Channel Inhibitors KCNN3, KCNN2, KCNN1 POLH 4814/4885MEN1 2831/4885KMT2A 483/4885
US-20220387615-A1 COMPOSITIONS COMPRISING ENZYME CLEAVABLE LINKER PLATFORMS AND CONJUGATES THEREOF ADAM17, ADAM8, ADAM33 POLH 2194/4885MEN1 1111/4885KMT2A 2529/4885
US-20090143317-A1 Quercetin Glycoside Composition and Method of Preparing the Same GANC, SI, AMY2A POLH 1184/4885MEN1 3245/4885KMT2A 4617/4885
US-20080182893-A1 Prevention, therapy atherosclerosis; prevent plaque destabilization; using ienzyme modified soquercitrin PCSK9, MMP1, IDE POLH 584/4885MEN1 4337/4885KMT2A 4051/4885
US-20070248700-A1 Extractions and Methods Comprising Elder Species NOP58, MYC, MDM4 POLH 2012/4885MEN1 3162/4885KMT2A 3205/4885
US-20090074708-A1 Inhibitors and Enhancers of Uridine Diphosphate-Glucuronosyltransferase 2B (UGT2B) UGT2B7, UGT2B17, UGT1A10 POLH 1551/4885MEN1 4841/4885KMT2A 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.