Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.41 |
| ▸ | PDE9A | O76083 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206499 | 0.82 | PDE2A (0.42) | PDE2AP2RX7LMNAPDE9AHPGD | |
| SCHEMBL13777964 | 0.79 | HPGD (0.45) | P2RX7LMNAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL22245241 | 0.77 | PDE9A (0.59) | P2RX7LMNAPDE9A | |
| SCHEMBL13780251 | 0.74 | APP (0.63) | PDE2ALMNAMAPTHPGDALDH1A1 | |
| SCHEMBL13106106 | 0.73 | P2RX7 (0.49) | PDE2AP2RX7LMNAPDE9AMAPT | |
| SCHEMBL13780252 | 0.72 | HPGD (0.41) | PDE2AP2RX7LMNAMAPTHPGD | |
| SCHEMBL21214764 | 0.72 | HPGD (0.45) | PDE2AP2RX7LMNAPDE9AMAPT | |
| SCHEMBL4208839 | 0.72 | PDE4A (0.41) | HPGDNPSR1 | |
| SCHEMBL13106540 | 0.72 | TRPM5 (0.60) | P2RX7PDE9AMAPT | |
| SCHEMBL13780274 | 0.68 | HPGD (0.51) | LMNAMAPTHPGDALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090182142-A1 | Aromatic Compound | FURUKUBO SHIGERU | 2009-07-16 | — | — | US | disclosed |
| US-20090182142-A1 | Aromatic Compound | FURUKUBO SHIGERU | 2009-07-16 | — | — | US | disclosed |
| US-20090182140-A1 | Alicyclic Heterocyclic Compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20090182140-A1 | Alicyclic Heterocyclic Compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-07-16 | — | — | US | disclosed |
| EP-1970373-A1 | ALICYCLIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-09-17 | — | — | EP | disclosed |
| EP-1956009-A1 | AROMATIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182140-A1 | Alicyclic Heterocyclic Compound | CCR4, CCR1, HRH4 | PDE2A 3624/4885P2RX7 812/4885LMNA 4047/4885 |
| US-20090182142-A1 | Aromatic Compound | HRH4, CCR4, HRH3 | PDE2A 3972/4885P2RX7 1212/4885LMNA 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.