Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SCN1A | P35498 | 2/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163242 | 0.88 | GPR35 (0.52) | GPR35NLRP3GAAALDH1A1L3MBTL1 | |
| SCHEMBL4620639 | 0.85 | GPR35 (0.50) | GPR35NLRP3GAAALDH1A1L3MBTL1 | |
| SCHEMBL7322003 | 0.84 | ALDH1A1 (0.54) | GPR35NLRP3GAAALDH1A1L3MBTL1 | |
| SCHEMBL18415563 | 0.83 | ALDH1A1 (0.59) | NLRP3GAAALDH1A1L3MBTL1MAPT | |
| SCHEMBL11445390 | 0.83 | GPR35 (0.67) | GPR35NLRP3GAAALDH1A1L3MBTL1 | |
| SCHEMBL22390769 | 0.83 | NLRP3 (0.61) | GPR35NLRP3GAAALDH1A1L3MBTL1 | |
| SCHEMBL23352324 | 0.82 | NLRP3 (0.59) | GPR35NLRP3GAAALDH1A1MAPT | |
| SCHEMBL9359788 | 0.81 | NLRP3 (0.78) | NLRP3ALDH1A1MAPTSCN3ALMNA | |
| SCHEMBL15144499 | 0.81 | GAA (0.73) | GPR35NLRP3GAAALDH1A1L3MBTL1 | |
| SCHEMBL31649002 | 0.81 | GAA (0.71) | GPR35GAAALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | GPR35 1625/4885NLRP3 3664/4885GAA 941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.