Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163242 | 0.86 | GPR35 (0.52) | GPR35GAANLRP3ALDH1A1KDM4E | |
| SCHEMBL13779378 | 0.85 | GPR35 (0.61) | GPR35GAANLRP3ALDH1A1MAPT | |
| SCHEMBL4729165 | 0.80 | KDM4E (0.67) | GPR35GAAALDH1A1KDM4EHPGD | |
| SCHEMBL7322003 | 0.74 | ALDH1A1 (0.54) | GPR35GAANLRP3ALDH1A1MAPT | |
| SCHEMBL11445390 | 0.73 | GPR35 (0.67) | GPR35GAANLRP3ALDH1A1MAPT | |
| SCHEMBL22390769 | 0.73 | NLRP3 (0.61) | GPR35GAANLRP3ALDH1A1KDM4E | |
| SCHEMBL14255616 | 0.73 | POLB (0.40) | GAAALDH1A1KDM4EL3MBTL1POLB | |
| SCHEMBL162716 | 0.72 | MAPT (0.51) | GPR35GAANLRP3ALDH1A1KDM4E | |
| SCHEMBL15144499 | 0.72 | GAA (0.73) | GPR35GAANLRP3ALDH1A1KDM4E | |
| SCHEMBL28066430 | 0.71 | GPR35 (0.49) | GPR35GAANLRP3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031549-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031548-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031549-A1 | PROCESS FOR THE PREPARATION OF ANTHRANILAMIDE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-03-20 | — | — | WO | disclosed |
| EP-1900730-A1 | Process for the preparation of anthranilamide derivatives | Syngeta Participations AG (CH) | 2008-03-19 | — | — | EP | disclosed |
| EP-1900730-A1 | Process for the preparation of anthranilamide derivatives | Syngeta Participations AG (CH) | 2008-03-19 | — | — | EP | disclosed |