Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | MAOB | P27338 | 11/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 5/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4823094 | 0.86 | TP53 (0.66) | NPC1MAOBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL17716806 | 0.80 | ALDH1A1 (0.49) | NPC1MAOBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL16383876 | 0.79 | ALDH1A1 (0.68) | NPC1MAOBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL17318526 | 0.77 | POLB (0.63) | NPC1MAOBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL28563825 | 0.77 | SMN1; SMN2 (0.74) | NPC1MAOBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL3923306 | 0.77 | KMT2A (0.51) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL1436180 | 0.77 | MAPT (0.68) | NPC1MAOBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL17712427 | 0.76 | KMT2A (0.71) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL893303 | 0.76 | KDM4E (1.00) | NPC1MAOBSMN1; SMN2RAB9AMEN1 | |
| SCHEMBL5672455 | 0.75 | NPC1 (0.67) | NPC1MAOBSMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | FORSCHUNGSVERBUND BERLIN E.V. (DE) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176773-A1 | Non-Peptidic Inhibitors of AKAP/PKA Interaction | PRKCH, AIP, PRKCE | NPC1 1716/4885MAOB 3179/4885SMN1; SMN2 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.