Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | MMP14 | P50281 | 1/20 | 0.54 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24518535 | 0.96 | FFAR1 (0.56) | MMP1MMP2MMP13MMP14MITF | |
| SCHEMBL29727858 | 0.96 | FFAR1 (0.56) | MMP1MMP2MMP13MMP14MITF | |
| SCHEMBL12417242 | 0.90 | FFAR1 (0.64) | RAB9ANPC1LMNAHTTFFAR1 | |
| SCHEMBL13236136 | 0.86 | FFAR1 (0.71) | MMP2LMNAFFAR1POLBALDH1A1 | |
| SCHEMBL9920145 | 0.81 | FFAR1 (0.53) | RAB9ASMN1; SMN2LMNAHPGDHTT | |
| SCHEMBL13446896 | 0.79 | MMP1 (0.73) | MMP1MMP2MMP13MMP14MITF | |
| SCHEMBL1903792 | 0.78 | MMP3 (0.55) | MMP13HPGDAKR1B1POLBALDH1A1 | |
| SCHEMBL1903789 | 0.78 | MMP3 (0.55) | MMP13HPGDAKR1B1POLBALDH1A1 | |
| SCHEMBL1903795 | 0.78 | MMP3 (0.55) | MMP13HPGDAKR1B1POLBALDH1A1 | |
| SCHEMBL26794059 | 0.77 | FFAR1 (0.59) | MMP2LMNAFFAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090175805-A1 | Neuraminidase Inhibitors and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090175805-A1 | Neuraminidase Inhibitors and uses thereof | ENGASE, NEU1, NEU2 | MMP1 171/4885MMP2 104/4885MMP13 155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.