Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727858 | 1.00 | FFAR1 (0.56) | FFAR1MMP1MMP2MMP13MMP14 | |
| SCHEMBL13780771 | 0.96 | MMP1 (0.54) | FFAR1MMP1MMP2MMP13MMP14 | |
| SCHEMBL13236136 | 0.90 | FFAR1 (0.71) | FFAR1MMP2LMNAKDM4EMAPT | |
| SCHEMBL12417242 | 0.86 | FFAR1 (0.64) | FFAR1LMNANPC1HTTRAB9A | |
| SCHEMBL26794059 | 0.81 | FFAR1 (0.59) | FFAR1MMP2LMNAKDM4EMAPT | |
| SCHEMBL29214808 | 0.80 | MMP1 (0.67) | FFAR1MMP1MMP2MMP13MMP14 | |
| SCHEMBL29214806 | 0.80 | MMP1 (0.67) | FFAR1MMP1MMP2MMP13MMP14 | |
| SCHEMBL26794068 | 0.78 | FFAR1 (0.46) | FFAR1LMNANPC1HPGDRAB9A | |
| SCHEMBL29727849 | 0.78 | FFAR1 (0.46) | FFAR1LMNANPC1HPGDRAB9A | |
| SCHEMBL26794066 | 0.77 | FFAR1 (0.58) | FFAR1LMNAKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
| US-20220185805-A1 | NOVEL COMPOUND MODULATING GSK-3 ACTIVITY | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2022-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185805-A1 | NOVEL COMPOUND MODULATING GSK-3 ACTIVITY | GSK3B, GSK3A, GSKIP | FFAR1 3524/4885MMP1 2929/4885MMP2 4186/4885 |
| US-11820764-B2 | Compound modulating GSK-3 activity | GSK3B, GSK3A, GSKIP | FFAR1 3450/4885MMP1 2835/4885MMP2 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.