Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417242 | 0.96 | FFAR1 (0.64) | FFAR1MAPTKDM4ELMNATHRB | |
| SCHEMBL26794059 | 0.91 | FFAR1 (0.59) | FFAR1MAPTKDM4ELMNATHRB | |
| SCHEMBL24518535 | 0.90 | FFAR1 (0.56) | FFAR1MAPTKDM4ELMNATHRB | |
| SCHEMBL29727858 | 0.90 | FFAR1 (0.56) | FFAR1MAPTKDM4ELMNATHRB | |
| SCHEMBL9920145 | 0.87 | FFAR1 (0.53) | FFAR1MAPTKDM4ELMNATHRB | |
| SCHEMBL26794066 | 0.87 | FFAR1 (0.58) | FFAR1MAPTKDM4ELMNATHRB | |
| SCHEMBL13780771 | 0.86 | MMP1 (0.54) | FFAR1LMNAPOLBMMP2ALDH1A1 | |
| SCHEMBL1903792 | 0.86 | MMP3 (0.55) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL1903795 | 0.86 | MMP3 (0.55) | MAPTKDM4EPOLBKMT2AMEN1 | |
| SCHEMBL1903789 | 0.86 | MMP3 (0.55) | MAPTKDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
| US-11820764-B2 | Compound modulating GSK-3 activity | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2023-11-21 | — | — | US | disclosed |
| US-20220185805-A1 | NOVEL COMPOUND MODULATING GSK-3 ACTIVITY | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2022-06-16 | — | — | US | disclosed |
| US-20220185805-A1 | NOVEL COMPOUND MODULATING GSK-3 ACTIVITY | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2022-06-16 | — | — | US | disclosed |
| US-20100190832-A1 | Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates | NATIONAL INSTITUTE OF IMMUNOLOGY. | 2010-07-29 | — | — | US | disclosed |
| US-20100190832-A1 | Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates | NATIONAL INSTITUTE OF IMMUNOLOGY. | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190832-A1 | Mechanism-based inhibitors of transthyretin amyloidosis: studies with biphenyl ethers and structural templates | TTR, TPR, POT1 | FFAR1 2539/4885MAPT 26/4885KDM4E 678/4885 |
| US-20220185805-A1 | NOVEL COMPOUND MODULATING GSK-3 ACTIVITY | GSK3B, GSK3A, GSKIP | FFAR1 3524/4885MAPT 700/4885KDM4E 778/4885 |
| US-11820764-B2 | Compound modulating GSK-3 activity | GSK3B, GSK3A, GSKIP | FFAR1 3450/4885MAPT 655/4885KDM4E 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.