Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.54 |
| ▸ | CDK2 | P24941 | 1/20 | 0.54 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.54 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29220747 | 0.76 | HCAR3 (0.71) | KMT2AMEN1HCAR3RAB9ANPC1 | |
| SCHEMBL13396455 | 0.76 | HDAC6 (0.58) | KMT2AMEN1CCNA2CDK2CCNA1 | |
| SCHEMBL7728110 | 0.75 | KMT2A (0.60) | KMT2AMEN1RAB9ANPC1KDM4E | |
| SCHEMBL6499835 | 0.73 | EGFR (0.65) | KMT2AMEN1CCNA2CDK2CCNA1 | |
| SCHEMBL29366822 | 0.73 | RAB9A (0.89) | KMT2AMEN1HCAR3RAB9ANPC1 | |
| SCHEMBL997866 | 0.73 | RAB9A (0.89) | KMT2AMEN1HCAR3RAB9ANPC1 | |
| SCHEMBL11128707 | 0.72 | MEN1 (0.56) | KMT2AMEN1CCNA2CDK2CCNA1 | |
| SCHEMBL4759340 | 0.72 | NPC1 (0.51) | KMT2AMEN1RAB9ANPC1HDAC6 | |
| SCHEMBL8425212 | 0.72 | — | — | |
| SCHEMBL821839 | 0.72 | KMT2A (1.00) | KMT2AMEN1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4791460-B2 | — | — | 2011-10-12 | — | — | JP | claimed |
| CN-116606246-A | Silver complex antibacterial agent with aromatic amide structure-containing nitrogen heterocyclic derivative as ligand, and preparation method and application thereof | 烟台哈尔滨工程大学研究院 | 2023-08-18 | — | — | CN | disclosed |
| EP-2300438-A1 | IMIDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH | Merck Sharp & Dohme Corp. (US) | 2011-03-30 | — | — | EP | disclosed |