Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5147853 | 0.88 | CYP3A4 (0.46) | ATMMEN1KMT2ACYP3A4LMNA | |
| SCHEMBL11669811 | 0.81 | HTT (0.51) | ATMMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL11663553 | 0.78 | ATM (0.40) | ATMMEN1KMT2AHTTCYP3A4 | |
| SCHEMBL11670172 | 0.78 | BCHE (0.58) | ATMMEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11880044 | 0.75 | SMN1; SMN2 (0.51) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4154636 | 0.74 | IDO1 (0.50) | ATMMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL22430335 | 0.74 | TSHR (0.48) | ATMMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL21058227 | 0.74 | ATM (0.48) | ATMMEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL11670010 | 0.74 | ALDH1A1 (0.52) | MEN1KMT2AHTTSMN1; SMN2CYP3A4 | |
| SCHEMBL9089179 | 0.74 | MEN1 (0.50) | ATMMEN1KMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| US-7247731-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-24 | — | — | US | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | THEM6, SOD1, SLC30A6 | ATM 4118/4885MEN1 1595/4885KMT2A 2881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.