Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1906473 | 0.84 | CLCN2 (0.53) | AKR1C3AKR1C2CYP2C19KDM4ELMNA | |
| SCHEMBL7223232 | 0.82 | KDM4E (0.54) | POLBKDM4E | |
| SCHEMBL769767 | 0.79 | ELANE (0.51) | PDK2ELANEPRTN3IDO1L3MBTL1 | |
| SCHEMBL8818967 | 0.79 | KMT2A (0.58) | PDK1PDK2PDK3PDK4ELANE | |
| SCHEMBL25449209 | 0.79 | AKR1C3 (0.66) | PDK1PDK2PDK3PDK4AKR1C3 | |
| SCHEMBL848499 | 0.77 | POLB (0.64) | PDK1PDK2PDK3PDK4AKR1C3 | |
| SCHEMBL31087257 | 0.77 | POLB (0.64) | PDK1PDK2PDK3PDK4AKR1C3 | |
| SCHEMBL522766 | 0.77 | AKR1C3 (0.50) | PDK1PDK2PDK3PDK4AKR1C3 | |
| SCHEMBL7363965 | 0.77 | AKR1C3 (0.50) | PDK1PDK2PDK3PDK4ELANE | |
| SCHEMBL27900539 | 0.77 | AKR1C3 (0.50) | PDK1PDK2PDK3PDK4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560565-B2 | Method for preparing derivatives of 3-hydroxypicolinic acid | BAYER CROPSCIENCE SA (FR) | 2009-07-14 | — | — | US | disclosed |