Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.50 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788818 | 0.82 | PDK1 (0.54) | KDM4EPOLB | |
| SCHEMBL1906473 | 0.82 | CLCN2 (0.53) | KDM4EALDH1A1CLCN2HPGDMEN1 | |
| SCHEMBL173853 | 0.81 | SIRT2 (0.49) | KDM4EALDH1A1SIRT2CLCN2HPGD | |
| SCHEMBL8818967 | 0.78 | KMT2A (0.58) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL769767 | 0.78 | ELANE (0.51) | KDM4EALDH1A1CLCN2HPGDSMN1; SMN2 | |
| SCHEMBL3078843 | 0.78 | KDM4E (0.72) | KDM4EALDH1A1SIRT2TNIKHPGD | |
| SCHEMBL704708 | 0.78 | KDM4E (0.62) | KDM4EALDH1A1SIRT2CLCN2HPGD | |
| SCHEMBL10424663 | 0.77 | SIRT2 (0.62) | KDM4EALDH1A1SIRT2CLCN2HPGD | |
| SCHEMBL9921482 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1SIRT2HPGDPDCD1 | |
| SCHEMBL175535 | 0.77 | KDM4E (0.56) | KDM4EALDH1A1SIRT2HPGDPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115819338-B | Preparation method of o-tertiary butyl amino benzamide derivative | 常州大学 | 2025-04-25 | — | — | CN | claimed |
| CN-115819338-A | Preparation method of o-tert-butylamino benzamide derivative | 常州大学 | 2023-03-21 | — | — | CN | claimed |
| CN-115819338-B | Preparation method of o-tertiary butyl amino benzamide derivative | 常州大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-115819338-B | Preparation method of o-tertiary butyl amino benzamide derivative | 常州大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-115819338-A | Preparation method of o-tert-butylamino benzamide derivative | 常州大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819338-A | Preparation method of o-tert-butylamino benzamide derivative | 常州大学 | 2023-03-21 | — | — | CN | disclosed |
| CN-115819338-A | Preparation method of o-tert-butylamino benzamide derivative | 常州大学 | 2023-03-21 | — | — | CN | disclosed |
| US-8236953-B2 | Process for preparing piper azine derivatives | GLAXO GROUP LIMITED (GB) | 2012-08-07 | — | — | US | disclosed |
| US-20110275815-A1 | BENZYLPIPERAZINE DERIVATIVES AS MOTILIN RECEPTOR ANTAGONISTS | SEAL JONATHAN THOMAS | 2011-11-10 | — | — | US | disclosed |
| US-6521603-B2 | Amide, thioamide, amidine and thioester derivatives containing a benzene, pyridine, thiophene, furan, pyrrole, pyrazole, thiazole or isothiazole ring | MONSANTO TECHNOLOGY LLC | 2003-02-18 | — | — | US | disclosed |
| US-6410558-B1 | USING INDOLE OR QUINOLINE COMPOUND | MONSANTO TECHNOLOGY LLC | 2002-06-25 | — | — | US | disclosed |
| US-5998466-A | PREPLANTING | MONSANTO COMPANY (US) | 1999-12-07 | — | — | US | disclosed |
| US-5849723-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| US-5834447-A | THIOPHENE DERIVATIVES | MONSANTO COMPANY (US) | 1998-11-10 | — | — | US | disclosed |
| US-5811411-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1998-09-22 | — | — | US | disclosed |
| US-5705513-A | HETEROCYCLIC FUNGICIDES WITH PYRIDINE OR FURAN RINGS | MONSANTO COMPANY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5693667-A | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1997-12-02 | — | — | US | disclosed |
| US-5498630-A | SUBSTITUTED BENZOTHIOPHENECARBOXAMIDES | MONSANTO COMPANY (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1993007751-A1 | FUNGICIDES FOR THE CONTROL OF TAKE-ALL DISEASE OF PLANTS | MONSANTO COMPANY (US) | 1993-04-29 | — | — | WO | disclosed |
| EP-0538231-A1 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275815-A1 | BENZYLPIPERAZINE DERIVATIVES AS MOTILIN RECEPTOR ANTAGONISTS | GPR68, GPR52, GPR88 | KDM4E 4252/4885ALDH1A1 3575/4885SIRT2 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.