Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 17/20 | 0.53 |
| ▸ | TCF7L2 | Q9NQB0 | 17/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606715 | 0.86 | CTNNB1 (0.64) | CTNNB1TCF7L2MAPTXDH | |
| SCHEMBL13797205 | 0.83 | CTNNB1 (0.68) | CTNNB1TCF7L2 | |
| SCHEMBL13797208 | 0.80 | CTNNB1 (0.73) | CTNNB1TCF7L2 | |
| SCHEMBL13797219 | 0.74 | MAPT (0.51) | CTNNB1TCF7L2MAPT | |
| SCHEMBL13797216 | 0.73 | CTNNB1 (0.64) | CTNNB1TCF7L2 | |
| SCHEMBL8889354 | 0.71 | SIRT5 (0.60) | CTNNB1TCF7L2MAPT | |
| SCHEMBL13797649 | 0.71 | MAPT (0.56) | CTNNB1TCF7L2MAPTXDH | |
| SCHEMBL30621767 | 0.71 | BRD4 (0.56) | MAPT | |
| SCHEMBL8899455 | 0.71 | BRD4 (0.56) | MAPT | |
| SCHEMBL13793556 | 0.71 | BRD4 (0.49) | CTNNB1TCF7L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |