Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796619 | 0.83 | CTNNB1 (0.52) | MAPTMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL13797650 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2APOLBRAB9A | |
| SCHEMBL14606715 | 0.78 | CTNNB1 (0.64) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13797658 | 0.78 | TDP1 (0.60) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13797202 | 0.77 | NPY5R (0.53) | SMN1; SMN2 | |
| SCHEMBL13797660 | 0.77 | ADRA2A (0.47) | MAPTMEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL13797653 | 0.75 | RXFP1 (0.56) | MAPTMEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL13797656 | 0.74 | ADORA3 (0.54) | MAPTMEN1KMT2ACYP3A4SMN1; SMN2 | |
| SCHEMBL13797657 | 0.73 | DGAT1 (0.54) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL13797641 | 0.73 | MEN1 (0.50) | MAPTMEN1KMT2ACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |