Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.66 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.66 |
| ▸ | FABP3 | P05413 | 1/20 | 0.66 |
| ▸ | PARP1 | P09874 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | PRKACG | P22612 | 1/20 | 0.52 |
| ▸ | PRKACB | P22694 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300140 | 0.91 | FABP4 (0.68) | FABP4FABP5FABP3PARP1KDM4E | |
| SCHEMBL8377270 | 0.84 | KDM4E (0.64) | PARP1KDM4EALDH1A1LCKPRKACA | |
| SCHEMBL11011279 | 0.83 | PARP1 (0.55) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4313671 | 0.81 | HPGD (0.68) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL150033 | 0.80 | FABP4 (1.00) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL30549325 | 0.80 | FABP4 (1.00) | FABP4FABP5FABP3KDM4EALDH1A1 | |
| SCHEMBL11009779 | 0.80 | ALDH1A1 (0.60) | FABP4FABP5PARP1ALDH1A1HPGD | |
| SCHEMBL11010372 | 0.80 | PARP1 (0.52) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL8272043 | 0.80 | PARP1 (0.55) | PARP1KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6294349 | 0.80 | PARP1 (0.52) | PARP1KDM4EALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009077173-A2 | DNA-ENCODED CHEMICAL LIBRARIES | PHILOCHEM AG (CH) | 2009-06-25 | — | — | WO | disclosed |