Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 3/20 | 0.68 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | PARP1 | P09874 | 6/20 | 0.56 |
| ▸ | FABP3 | P05413 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PRKACA | P17612 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | PRKACG | P22612 | 1/20 | 0.50 |
| ▸ | PRKACB | P22694 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13799882 | 0.91 | FABP4 (0.66) | FABP4FABP5KDM4EPARP1FABP3 | |
| SCHEMBL11009779 | 0.84 | ALDH1A1 (0.60) | FABP4FABP5MAPK1PARP1ALDH1A1 | |
| SCHEMBL97551 | 0.82 | MAPK1 (0.70) | FABP4FABP5KDM4EHSD17B10MAPK1 | |
| SCHEMBL7298333 | 0.82 | ALDH1A1 (0.55) | FABP4FABP5MAPK1PARP1ALDH1A1 | |
| SCHEMBL30530511 | 0.82 | MAPK1 (0.70) | FABP4FABP5KDM4EHSD17B10MAPK1 | |
| SCHEMBL8377270 | 0.82 | KDM4E (0.64) | KDM4EMAPK1PARP1ALDH1A1LCK | |
| SCHEMBL7308089 | 0.82 | TNF (0.62) | KDM4EHSD17B10PARP1CTNNB1 | |
| SCHEMBL4314440 | 0.81 | FABP4 (1.00) | FABP4FABP5KDM4EHSD17B10MAPK1 | |
| SCHEMBL30573159 | 0.81 | FABP4 (1.00) | FABP4FABP5KDM4EHSD17B10MAPK1 | |
| SCHEMBL7299674 | 0.81 | KDM4E (0.48) | FABP4FABP5KDM4EHSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304560-A | Treating CNS disorders; dopamine receptor antagonist | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| EP-0481342-A1 | Quinazoline derivatives and their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |