Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 9/20 | 0.41 |
| ▸ | DRD4 | P21917 | 8/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7218584 | 0.99 | HTR7 (0.43) | HTR7DRD3DRD4DRD2TGFBR1 | |
| SCHEMBL13800744 | 0.95 | DRD3 (0.44) | HTR7DRD3DRD4DRD2TGFBR1 | |
| Hydrochloric Acid SCHEMBL7225224 | 0.94 | DRD3 (0.43) | HTR7DRD3DRD4DRD2TGFBR1 | |
| SCHEMBL13800604 | 0.92 | TGFBR1 (0.43) | HTR7DRD4TGFBR1ACVR1HCRTR1 | |
| SCHEMBL13800341 | 0.92 | HTR7 (0.43) | HTR7DRD3DRD4DRD2TGFBR1 | |
| SCHEMBL13800778 | 0.92 | HTR7 (0.46) | HTR7DRD4TGFBR1ACVR1HCRTR1 | |
| SCHEMBL13800750 | 0.92 | HTR7 (0.52) | HTR7DRD3DRD4DRD2BCHE | |
| SCHEMBL13800723 | 0.92 | HTR7 (0.41) | HTR7DRD3DRD4DRD2TGFBR1 | |
| SCHEMBL13800622 | 0.92 | CYP3A4 (0.46) | HTR7TGFBR1ACVR1BCHEBACE1 | |
| Hydrochloric Acid SCHEMBL7217819 | 0.92 | TGFBR1 (0.42) | HTR7DRD4TGFBR1ACVR1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | KOWA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | KOWA CO., LTD. (JP) | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143430-A1 | ERYTHROPOIETIN PRODUCTION ACCELERATOR | EPOR, GHRHR, ARL1 | HTR7 3747/4885DRD3 1731/4885DRD4 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.